CD11b antibody (M1/70) [PE]

Integrin alpha-M
CD11 antigen-like family member B
CR-3 alpha chain
Cell surface glycoprotein MAC-1 subunit alpha
Leukocyte adhesion receptor MO1
CD_antigen: CD11b
Gene name: ITGAM, CD11B, CR3A
MO1A, MAC-1, MAC1A, SLEB6
As low as $380.70
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00114381
CD11b antibody (M1/70) [PE]
More Information
ID Covalab mab20633
Product type Primary antibodies
Clonality Monoclonal antibody
Clone M1/70
Isotype IgG2b
Raised in Rat
Immunogen B10 mouse spleen cells enriched for T cells
Activity cross reaction Reacts with human, monkey, mouse and rabbit CD11b.
Species Hu, Mk, Ms, Rab
Labelling PE
Form Purified (liquid chromatography)
Preservative NaN3 15 mM
Storage instructions Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Target CD11b
Uniprot ID P11215
Gene ID 3684
Applications FA, FC, IHC - F, IP
Working dilutions Optimal dilutions should be determined by the end user.
The following are guidelines only:
FC (0.5 µg/ml)
Publication *Takagi H et al. Cooperation of specific ICAM-3 grabbing nonintegrin-related 1 (SIGNR1) and complement receptor type 3 (CR3) in the uptake of oligomannose-coated liposomes by macrophages. Glycobiology. 2009 Mar,19(3):258-66.
*Leon F et al. Antibodies to complement receptor 3 treat established inflammation in murine models of colitis and a novel model of psoriasiform dermatitis. J Immunol. 2006 Nov 15,177(10):6974-82.
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