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Cartilage oligomeric matrix protein antibody

Thrombospondin-5 (TSP5)
Gene name: COMP
Play a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin. Play a role in the pathogenesis of osteoarthritis. Suppressor of apoptosis in both primary chondrocytes and transformed cells. Suppresses apoptosis by blocking the activation of caspase-3 and by inducing the IAP family of survival proteins (BIRC3, BIRC2, BIRC5 and XIAP).

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Product Code pab0027-P
Immunogen A 16 residue synthetic peptide derived from specific domain of Complexe Oligomatrix Protein
Target Specificity Reacts with human COMP from cartilage matrix.
Name Cartilage oligomeric matrix protein (COMP)
Uniprot ID P49747
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human
Labelling None
Appearance Lyophilized powder
Conc. / Activity 1 mg/ml
Form Purified (protein A)
Constituents Tris 0,1M, glycine 0,1M, sucrose 2%
Preservatives None
Recommendations Must be reconstituted in distilled water.
Storage Lyophilized powder stable for a minimum of 2 years at -20°C.
Store reconstituted antibodies at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Applications Western Blot, Immunohistochemistry, ELISA
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC 1:200 - 1:1000
WB 1:200 - 1:1000
Research areas Cell biology
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Cartilage oligomeric matrix protein antibody

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