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Carbohydrate-responsive element-binding protein antibody

Class D basic helix-loop-helix protein 14 (bHLHd14)
MLX interactor
MLX-interacting protein-like
WS basic-helix-loop-helix leucine zipper protein (WS-bHLH)
Williams-Beuren syndrome chromosomal region 14 protein
Gene name: MLXIPL, BHLHD14, MIO, WBSCR14
ChREBP is a transcription factor involved in activating genes that encode enzymes of fatty acid biosynthesis in liver and adipose.This protein may have relevance to lipid metabolism, obesity, and type II diabetes.

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Product Code pab50149
Immunogen C-terminal synthetic peptide made to the human ChREBP protein sequence (between residues 800-852). [Uniprot# Q9NP71, isoform 1/alpha]
Target Specificity Reacts with human ~93 kDa ChREBP. May cross react with protein from mouse and rat (83% sequence homology). Not tested in other species.
Name Carbohydrate-responsive element-binding protein (ChREBP)
Uniprot ID Q9NP71
Gene ID 51085
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human, Mouse, Rat
Labelling None
Appearance Liquid
Conc. / Activity 1 mg/ml
Form Antigen affinity purified
Constituents Tris-citrate/phosphate, pH 7-8
Preservatives NaN3 0.01%
Storage Short term storage at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Applications Western Blot, IHC - Paraffin sections, Immunofluorescence, Immunocytochemistry, Immunoprecipitation, Chromatin IP
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
ChIP (1:10 - 1:500)
ICC/ IF (1:100 - 1:500)
IHC - P (1:100)
IP (1:10 - 1:500)
WB (1:1000)
Research areas Chromatin,Lipidomics
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WB - Carbohydrate-responsive element-binding protein antibody<br/>(pab50149)<br/>Anti-CHREBP antibody WB staining of 20 µg of human hepatocyte lysate.

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