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Breast cancer type 1 susceptibility protein antibody (KEN)

Breast cancer type 1 susceptibility protein
RING finger protein 53
DNA repair associated
Gene name: BRCA1, RNF53, IRIS, PSCP, BRCAI, BRCC1, FANCS, PNCA4, BROVCA1, PPP1R53
Breast cancer type 1 susceptibility protein antibody (KEN)

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Product Code mab50131
Clone KEN
Immunogen Human BRCA1 residues 1314-1864.
The epitope recognized is found between amino acids 1314-1600.
Target Specificity Reacts with human BRCA1.
Name Breast cancer type 1 susceptibility protein
Uniprot ID P38398
Gene ID 672
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Product type Primary antibodies
Clonality Monoclonal antibody
Isotype IgG3 / Kappa
Produced in Mouse
Species Human
Labelling None
Appearance Liquid
Conc. / Activity 1,67 mg/ml
Form Purified (protein A)
Constituents Tris-glycine, NaCl 150 mM
Preservatives NaN3 0.05%
Storage Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
Applications Western Blot, Immunofluorescence, Immunocytochemistry, Immunoprecipitation
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
ICC/ IF (1:100)
IP (1:50 - 1:500)
WB (2 - 4 µg/ml)
Research areas Cancer,Cell biology,Chromatin,Nuclear signaling
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ICC - Breast cancer type 1 susceptibility protein antibody (KEN)<br/>(mab50131)<br/>Anti-BRCA1 antibody ICC staining (green) of MCF-7 cells. Nuclei (Dapi) and alpha-tubulin were counterstained in blue and red.

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