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Beclin-1 antibody

Coiled-coil myosin-like BCL2-interacting protein
Protein GT197
Gene name: BECN1, GT197
Plays a central role in autophagy. Required for the abcission step in cytokinesis. May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.

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Ref : 00016635

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Product Code pab50126
Immunogen Internal synthetic peptide to human Beclin 1, containing residues within 1-100
This sequence has 94% identity with the mouse sequence and 88% identity with the rat sequence
Target Specificity Reacts with human ~52 kDa Beclin 1 protein. Cross-reacts with mouse and rat protein.
Name Beclin-1
Uniprot ID Q14457
Gene ID 8678
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human, Mouse, Rat
Labelling None
Appearance Liquid
Conc. / Activity 1.15 mg/ml
Form Antigen affinity purified
Constituents PBS, Glycerol 30 %
Preservatives NaN3 0.05%
Storage Store at 4°C. Do not freeze.
Applications Western Blot, IHC - Paraffin sections, Immunofluorescence, Immunocytochemistry, Immunoprecipitation
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
ICC/IF: 1:50 - 1:200
IHC - P : 1:400
IP : 1/80
WB : 1:500 - 1:2000
Research areas Autophagy,Cancer,Immunology,Nuclear signaling,Virology
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WB : Beclin-1 antibody<br/>(pab50126)<br/>Anti-Beclin-1 antibody WB staining of mouse liver tissue lysate (50 ug). Antibody pab50126 dilution 1.15 mg/ml.

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