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BCL2 / Bcl-2 (Ser70) antibody

B-cell CLL/lymphoma 2, B-cell lymphoma protein 2, Bcl-2
Gene name: BCL2, PPP1R50
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).

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Ref : 00019049

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Product Code pab71957
Immunogen Synthetic peptide surrounding Serine 70 from human BCL2 / Bcl-2.
Target Specificity Reacts with human BCL2
Name Apoptosis regulator Bcl-2
Uniprot ID P10415
Gene ID 596
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Product type Primary antibodies
Clonality Polyclonal antibody
Isotype IgG
Produced in Rabbit
Species Human
Labelling None
Appearance Liquid
Conc. / Activity 1 mg/ml
Form Antigen affinity purified
Constituents PBS, glycerol 50%
Preservatives NaN3 0.02%
Storage +4°C or -20°C, Avoid repeated freezing and thawing.
Applications Western Blot, IHC - Paraffin sections, Immunofluorescence
Working dilutions IHC-P (10 µg/ml)
Research areas Apoptosis,Autophagy,Immunology
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IHC : BCL2 / Bcl-2 (Ser70) antibody<br/>(pab71957)<br/>Anti-BCL2 / Bcl-2 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody pab71957 concentration 10 µg/ml

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