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BCL2 / Bcl-2 (Internal) antibody

B-cell CLL/lymphoma 2, B-cell lymphoma protein 2, Bcl-2, PPP1R50
Gene name: BCL2
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).

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€360.00
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Ref : 00023115

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Product Code pab73966
Immunogen Synthetic peptide from human BCL-2 (aa46-95).
Target Specificity Reacts with human BCL2 / Bcl-2. Cross reacts with mouse and rat protein.
Name Apoptosis regulator Bcl-2
Uniprot ID P10415
Gene ID 596
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Product type Primary antibodies
Clonality Polyclonal antibody
Isotype IgG
Produced in Rabbit
Species Human, Mouse, Rat
Labelling None
Appearance Liquid
Conc. / Activity 1 mg/ml
Form Antigen affinity purified
Constituents PBS (without Mg2+, Ca2+), pH 7.4, NaCl 150 mM, glycerol 50%
Preservatives NaN3 0.02%
Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
Applications Western Blot, IHC - Paraffin sections, Immunofluorescence, ELISA
Working dilutions ELISA (1:10000), IF (1:100 - 1:500), IHC-P (1:100), WB (1:500 - 1:1000)
Research areas Apoptosis,Autophagy,Immunology
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IHC : BCL2 / Bcl-2 (Internal) antibody<br/>(pab73966)<br/>Anti-BCL2 / Bcl-2 antibody IHC staining of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody pab73966 dilution 1

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