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BCL2 / Bcl-2 antibody

B-cell CLL/lymphoma 2, B-cell lymphoma protein 2, Bcl-2
Gene name: BCL2, PPP1R50
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).

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€360.00
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Ref : 00026450

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Product Code pab75275
Immunogen Recombinant human protein purified from E. coli (His-Bcl-2 1-211 a.a.).
Target Specificity Reacts with human BCL2 / Bcl-2.
Name Apoptosis regulator Bcl-2
Uniprot ID P10415
Gene ID 596
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Product type Primary antibodies
Clonality Polyclonal antibody
Isotype IgG
Produced in Rabbit
Species Human
Labelling None
Appearance Liquid
Form Purified (protein A)
Constituents HEPES, 0.15M NaCl, 0.01% BSA, 50% glycerol
Preservatives 0.03% NaN3
Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
Applications Western Blot, IHC - Paraffin sections
Working dilutions IHC - P (1:100), WB (1:2000)
Research areas Apoptosis,Autophagy,Immunology
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IHC : BCL2 / Bcl-2 antibody<br/>(pab75275)<br/>Anti-BCL2 / Bcl-2 antibody IHC staining of human spleen, lymphocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody pab75275 dilution 1:100.

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