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BAX (N-Terminus) antibody

Apoptosis regulator BAX
Bcl-2-like protein 4, Bcl2-L-4, bcl2-associated x protein
Gene name: BAX, BCL2L4
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.

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Ref : 00025725

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Product Code pab74913
Immunogen Synthetic peptide from N-terminal part of mouse BAX.
Target Specificity Reacts with the N-terminus part of mouse BAX. Cross reacts with human and rat protein.
Name BAX
Uniprot ID Q07812
Gene ID 581
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Product type Primary antibodies
Clonality Polyclonal antibody
Isotype IgG
Produced in Rabbit
Species Human, Mouse, Rat
Labelling None
Appearance Liquid
Form Purified
Constituents PBS, pH 7.2, 0.2% gelatin
Preservatives 0.09% NaN3
Storage Store undiluted at 4 degrees C. Do not freeze.
Applications Western Blot, IHC - Paraffin sections, Immunoprecipitation
Working dilutions IHC - P (1:50), IP, WB (2 µg/ml)
Research areas Apoptosis,Autophagy,Immunology,PI3K | AKT | mTOR
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IHC : BAX (N-Terminus) antibody<br/>(pab74913)<br/>Anti-BAX antibody IHC staining of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody pab74913 dilution 1:50.

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