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BAX (N-Terminus) antibody

Apoptosis regulator BAX, BCL2-associated X protein
Bcl-2-like protein 4, Bcl2-L-4
Gene name: BAX, BCL2L4
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.

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€360.00
Available
Ref : 00025686

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Product Code pab74874
Immunogen Synthetic peptide corresponding to 16 amino acids near the amino-terminus of human Bax.
Target Specificity Reacts with the N-terminus part of human BAX.
Name BAX
Uniprot ID Q07812
Gene ID 581
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human
Labelling None
Appearance Liquid
Conc. / Activity 1 mg/ml
Form Purified
Constituents PBS
Preservatives 0.02% NaN3
Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
Applications Western Blot, IHC - Paraffin sections, Immunocytochemistry
Working dilutions ICC, IHC - P (5 µg/ml), WB (2 µg/ml)
Research areas Apoptosis,Autophagy,Immunology,PI3K | AKT | mTOR
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IHC : BAX (N-Terminus) antibody<br/>(pab74874)<br/>Anti-BAX antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody pab74874 concentration 2 ug/ml.

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