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BAX (6A7) antibody

Apoptosis regulator BAX, BCL2-associated X protein
Bcl-2-like protein 4, Bcl2-L-4
Gene name: BAX, BCL2L4
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.

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Ref : 00028002

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Product Code mab71211
Clone 6A7
Immunogen Synthetic peptide from human BAX.
Target Specificity Reacts with human BAX. Cross reacts with monkey, mouse and rat protein.
Name BAX
Uniprot ID Q07812
Gene ID 581
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Product type Primary antibodies
Clonality Monoclonal antibody
Isotype IgG1
Produced in Mouse
Species Human, Mouse, Rat, Monkey
Labelling None
Appearance Liquid
Form Purified
Constituents PBS, pH 7.2
Preservatives 0.09% NaN3 at 0.5 mg/ml
Storage Store at +4°C. Store undiluted.
Applications Western Blot, IHC - Paraffin sections, Immunoprecipitation
Working dilutions IHC-P (10 - 12 µg/ml)
Research areas Apoptosis,Autophagy,Immunology,PI3K | AKT | mTOR
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IHC : BAX (6A7) antibody<br/>(mab71211)<br/>Anti-BAX antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody mab71211 concentration 10 µg/ml.

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