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BACE2 (aa44-59) antibody

Beta-secretase 2
Aspartic-like protease 56 kDa
Aspartyl protease 1 (ASP1) (Asp 1)
Beta-site amyloid precursor protein cleaving enzyme 2 (Beta-site APP cleaving enzyme 2)
Down region aspartic protease (DRAP)
Membrane-associated aspartic protease 1
BACE2, AEPLC, ALP56, APL56, ASP21, BAE2, Beta-site amyloid beta A4 precursor protein-cleaving enzyme 2, CDA13, CEAP1
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.

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Product Code pab75121
Immunogen Synthetic peptide from human BACE2.
Target Specificity Reacts with human BACE2. Cross reacts with mouse and rat protein.
Name BACE2
Uniprot ID Q9Y5Z0
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human, Mouse, Rat
Labelling None
Appearance Liquid
Conc. / Activity 1 mg/ml
Form Purified
Constituents PBS
Preservatives 0.02% NaN3
Storage +4°C or -20°C, Avoid repeated freezing and thawing.
Applications Western Blot, IHC - Paraffin sections
Working dilutions IHC - P (20 µg/ml), WB
Research areas Neurology,Signal transduction,Vesicle trafficking
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BACE2 (aa44-59) antibody<br/>(pab75121)<br/>Anti-BACE2 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 µg/ml.

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