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AXIN1 (C-Terminus) antibody

Axin-1
Axis inhibition protein 1 (hAxin)
AXIN1, AXIN, MGC52315
Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects; down-regulates CTNNB1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway.

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€360.00
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Ref : 00020205

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Product Code pab72528
Immunogen Synthetic peptide C-FEEKIIGKVEKVD from the C-terminus of human AXIN1 (NP_003493.1; NP_851393.1). Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Gibbon (100%), Baboon (100%), Monkey (100%), Marmoset (100%)
Target Specificity Reacts with the C-terminus part of human AXIN1. Cross reacts with bovine, canine, mouse and rat protein. This antibody is expected to recognise both reported isoforms.
Name AXIN1
Accession Number O15169
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Goat
Species Human, Mouse, Rat, Bovine, Canine
Labelling None
Appearance Liquid
Conc. / Activity 0.5 mg/ml
Form Antigen affinity purified
Constituents TBS, pH 7.3, BSA 0.5%
Preservatives NaN3 0.02%
Storage Store at -20°C. Minimize freezing and thawing.
Applications IHC - Paraffin sections, ELISA
Working dilutions ELISA (1:128000), IHC-P (3.75 µg/ml)
Research areas Apoptosis,Neurology,Signal transduction
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IHC : AXIN1 (C-Terminus) antibody<br/>(pab72528)<br/>Anti-AXIN1 / AXIN antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 75 µg/ml.

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