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ATG7 (C-Terminus) antibody

Ubiquitin-like modifier-activating enzyme ATG7
ATG12-activating enzyme E1 ATG7
Autophagy-related protein 7 (APG7-like) (hAGP7)
Ubiquitin-activating enzyme E1-like protein
Gene name: ATG7, APG7-LIKE, APG7L, DKFZp434N0735, GSA7
Functions as an E1 enzyme essential for multisubstrates such as ATG8-like proteins and ATG12. Forms intermediate conjugates with ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A). PE-conjugation to ATG8-like proteins is essential for autophagy. Also acts as an E1 enzyme for ATG12 conjugation to ATG5 and ATG3

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orders@covalab.com - tel: +33 (0) 437 654 230 - fax: +33 (0) 437 289 416

€360.00
Available
Ref : 00015827

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Product Code pab70356
Immunogen Synthetic peptide from human ATG7.
Target Specificity Reacts with 17 amino acid peptide from near the carboxy terminus of human APG7.
Name ATG7
Uniprot ID O95352
Gene ID 10533
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human, Mouse
Labelling None
Appearance Liquid
Conc. / Activity 1 mg/ml
Form Antigen affinity purified
Constituents PBS
Preservatives NaN3 0.02%
Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
Applications Western Blot, IHC - Paraffin sections, Immunocytochemistry
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC - P (5 µg/ml),
WB (0.5 - 1 µg/ml)
Research areas Autophagy,Synthesis and degradation
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IHC : ATG7 (C-Terminus) antibody<br/>(pab70356)<br/>Anti-ATG7 antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody pab70356 concentration 5 ug/ml.

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