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ATG5 antibody

ATG5
Autophagy protein 5, APG5-like,
Apoptosis-specific protein
Gene name: ATG5, APG5, APG5-LIKE, APG5L, ASP, hAPG5
Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after oxidative damage, and in subsequent cellular longevity.

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€360.00
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Product Code pab72230
Immunogen Synthetic peptide from human ATG5 (amino acid 1-50).
Target Specificity Reacts with APG5L from human, bovine, mouse, pufferfish, porcine, rat and zebrafish
Name ATG5
Uniprot ID Q9H1Y0
Gene ID 9474
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human, Mouse, Rat, Mammal, Zebrafish, Pufferfish
Labelling None
Appearance Liquid
Conc. / Activity 0.5 mg/ml
Form Antigen affinity purified
Constituents PBS, gelatin 0.2%
Preservatives NaN3 0.05%
Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
Applications IHC - Paraffin sections, Immunofluorescence
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC-P (5 µg/ml),
Research areas Autophagy,Cancer,Cardiac and vascular biomarkers
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IHC - ATG5 antibody<br/>(pab72230)<br/>Anti-ATG5 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-<br/>embedded tissue after heat-induced antigen retrieval. Antibody pab72230 concentration 5 µg/ml.

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