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ATG4B antibody

Cysteine protease ATG4B, AUT-like 1 cysteine endopeptidase, Autophagin-1, Autophagy-related cysteine endopeptidase 1, Autophagy-related protein 4 homolog B, hAPG4B
Gene name: ATG4B, APG4B, AUTL1, MGC1353, KIAA0943
Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy.

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€360.00
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Ref : 00024152

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Product Code pab74475
Immunogen Synthetic peptide from human ATG4B.
Target Specificity Reacts with human ATG4B. Cross reacts with chicken, xenopus, mouse, pufferfish, rat and zebrafish protein.
Name ATG4B
Uniprot ID Q9Y4P1
Gene ID 23192
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Product type Primary antibodies
Clonality Polyclonal antibody
Isotype IgG
Produced in Rabbit
Species Human, Mammal, Chicken, Zebrafish, Xenopus
Labelling None
Appearance Liquid
Conc. / Activity 0.5 mg/ml
Form Purified (protein G)
Constituents PBS, 0.2% gelatin
Preservatives NaN3 0.05%
Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
Applications Western Blot, IHC - Paraffin sections
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC-P (10 µg/ml),
WB (1 - 3 µg/ml)
Research areas Autophagy
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IHC : ATG4B antibody<br/>(pab74475)<br/>Anti-ATG4B antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody pab74475 concentration 10 µg/ml.

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