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ATG16L1 (Internal) antibody

Autophagy-related protein 16-1
APG16-like 1
Gene name: ATG16L1, APG16L, ATG16A, ATG16L, FLJ00045, FLJ10035, FLJ10828, FLJ22677, IBD10, WDR30
Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.

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€360.00
Available
Ref : 00015825

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Product Code pab70354
Immunogen 18 amino acid peptide from near the center of human ATG16.
Target Specificity Reacts with ATG16L1 from human, mouse and rat
Name ATG16L1
Uniprot ID Q676U5
Gene ID 55054
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human, Mouse, Rat
Labelling None
Appearance Liquid
Conc. / Activity 1 mg/ml
Form Antigen affinity purified
Constituents PBS
Preservatives NaN3 0.02%
Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
Applications Western Blot, IHC - Paraffin sections, Immunofluorescence, Immunocytochemistry, ELISA
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC - P 5 µg/ml,
WB 0.25 - 0.5 µg/ml
ICC 2 µg/ml,
IF 4 µg/ml
Research areas Autophagy,Vesicle trafficking
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IHC : ATG16L1 (Internal) antibody<br/>(pab70354)<br/>Anti-ATG16L1 antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed,<br/>paraffin-embedded tissue after heat-induced antigen retrieval. Antibody pab70354 concentration 5 ug/ml.

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