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APAF1 / APAF-1 (C-Terminus) antibody

Apoptotic protease-activating factor 1, APAF-1
Gene name: APAF1, KIAA0413, CED4, DKFZp781B1145
Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.

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Ref : 00020618

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Product Code pab72741
Immunogen A synthetic peptide derived from the C-terminus of human Apaf-1.
Target Specificity Reacts with human, mouse and rat APAF1 / APAF-1.
Name APAF1 / APAF-1
Uniprot ID O14727
Gene ID 317
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human, Mouse, Rat
Labelling None
Appearance Liquid
Conc. / Activity 0.2 mg/ml
Form Antigen affinity purified
Constituents PBS 10 mM, pH 7.4, BSA
Preservatives NaN3
Storage Store at 2°C to 8°C degrees. Do not freeze.
Applications IHC - Paraffin sections
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only:
IHC-P (10 µg/ml)
Research areas Apoptosis
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IHC - APAF1 / APAF-1 (C-Terminus) antibody<br/>(pab72741)<br/>Anti-APAF1 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 µg/ml.

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