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ANAPC11 / APC11 (Internal) antibody

Anaphase-promoting complex subunit 11 (APC11)
Cyclosome subunit 11
Hepatocellular carcinoma-associated RING finger protein
ANAPC11, APC11, Apc11p, HSPC214, MGC882
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.

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€360.00
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Ref : 00015785

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Product Code pab70314
Immunogen 18 amino acid peptide near the center of human APC11.
Target Specificity Reacts with human ANAPC11
Name ANAPC11 / APC11
Accession Number Q9NYG5
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human, Mouse, Rat
Labelling None
Appearance Liquid
Conc. / Activity 1 mg/ml
Form Antigen affinity purified
Constituents PBS
Preservatives NaN3 0.02%
Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
Applications Western Blot, IHC - Paraffin sections, ELISA
Working dilutions ELISA, IHC - P (5 µg/ml), WB (1 - 2 µg/ml)
Research areas Cell cycle
Print datasheet

IHC : ANAPC11 / APC11 (Internal) antibody<br/>(pab70314)<br/>Anti-ANAPC11 / APC11 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 µg/ml.

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