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Alpha-synuclein phosphoserine 129 (SNCA-pS129) antibody

α-synuclein, Alpha-synuclein phosphoserine 129, SCNA pS129
Non-A beta component of AD amyloid
Non-A4 component of amyloid precursor, NACP
Gene name : SNCA, NACP, PARK1
May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.

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Product Code pab0829-P
Immunogen Synthetic peptide derived from C-ter domain of human Alpha-synuclein containing a phosphoserine at position 129.
Target Specificity Reacts with human Alpha-synuclein pS129. Cross-reacts with rat, mouse and other species due to sequence homology.
Name Alpha-synuclein phosphoserine 129 (SCNA pS129)
Uniprot ID P37840
Gene ID 6622
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human, Mouse, Rat
Labelling None
Appearance Lyophilized powder
Conc. / Activity 1 mg/ml
Form Purified (protein A)
Constituents Tris 0,1M, glycine 0,1M, sucrose 2%
Preservatives None
Recommendations Must be reconstituted in distilled water.
Storage Lyophilized powder stable for a minimum of 2 years at -20°C.
Store reconstituted antibodies at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Applications Western Blot, Immunofluorescence, ELISA
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
IF (1:50 - 1:500)
WB (1:200 - 1:1000)
Research areas Disease-related biomarkers,Neurology
Print datasheet

Alpha-synuclein phosphoserine 129 (SNCA-pS129) antibody

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