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Adiponectin (C-Terminus) antibody

30 kDa adipocyte complement-related protein
Adipocyte complement-related 30 kDa protein (ACRP30)
Adipocyte, C1q and collagen domain-containing protein
Adipose most abundant gene transcript 1 protein (apM-1)
Gelatin-binding protein
Gene name : ADIPOQ, ACDC, ACRP30, APM1, GBP28

Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.

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Ref : 00015743

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Product Code pab70272
Immunogen Synthetic peptide from human ADIPOQ / Adiponectin.
Target Specificity Reacts with 15 amino acid peptide from near the carboxy-terminus of human adiponectin
Name Adiponectin
Accession Number Q15848
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human, Mouse, Rat
Labelling None
Appearance Liquid
Conc. / Activity 1 mg/ml
Form Antigen affinity purified
Constituents PBS
Preservatives NaN3 0.02%
Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
Applications Western Blot, IHC - Paraffin sections
Working dilutions IHC - P (2.5 µg/ml), WB (1 µg/ml)
Research areas Lipidomics,Signal transduction
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IHC : Adiponectin (C-Terminus) antibody<br/>(pab70272)<br/>Anti-Adiponectin antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 µg/ml.

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