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ADAMTS5 (Metalloprotease Domain) antibody

A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAM-TS 5) ADAM-TS5)
A disintegrin and metalloproteinase with thrombospondin motifs 11 (ADAM-TS 11) (ADAMTS-11)
Gene name : ADAMTS5, ADAMTS11, ADMP2
Adamts-5, FLJ36738
Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. May play a role in proteolytic processing mostly during the peri-implantation period.

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Ref : 00015656

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Product Code pab70263
Immunogen Synthetic 18 amino acid peptide from Metalloprotease domain of human ADAMTS5. Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Gibbon (100%), Monkey (100%), Marmoset (100%), Mouse (100%), Rat (100%), Hamster (100%)
Target Specificity Reacts with human ADAMTS5. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Accession Number Q9UNA0
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human
Labelling None
Appearance Liquid
Conc. / Activity 1 mg/ml
Form Antigen affinity purified
Constituents PBS
Preservatives NaN3 0.1%
Storage Long term: -70°C; Short term: +4°C
Applications IHC - Paraffin sections
Working dilutions IHC - P (3 )
Research areas Developmental biology,Inflammation
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IHC : ADAMTS5 (Metalloprotease Domain) antibody<br/>(pab70263)<br/>Anti-ADAMTS5 antibody IHC of human cartilage. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

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