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ADAMTS4 (Internal) antibody

A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAM-TS 4) (ADAM-TS4) (ADAMTS-4)
ADMP-1
Aggrecanase-1
Gene name : ADAMTS4, KIAA0688
ADAMTS-2
Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the '392-Glu-|-Ala-393' site.

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€360.00
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Ref : 00015649

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Product Code pab70256
Immunogen Synthetic 19 amino acid peptide from internal region of human ADAMTS4. Percent identity with other species by BLAST analysis: Human (100%), Orangutan (100%), Gibbon (100%), Marmoset (100%), Dog (100%), Bat (100%), Panda (100%), Horse (100%)
Target Specificity Reacts with human ADAMTS4. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except ADAMTS8 (53%).
Name ADAMTS4
Accession Number O75173
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human
Labelling None
Appearance Liquid
Conc. / Activity 1 mg/ml
Form Antigen affinity purified
Constituents PBS
Preservatives NaN3 0.1%
Storage Store at 4°C for short term applications. For long term storage, aliquot and store at -20°C.
Applications IHC - Paraffin sections
Working dilutions IHC - P (2.6 µg/ml)
Research areas Disease-related biomarkers,Inflammation
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IHC : ADAMTS4 (Internal) antibody<br/>(pab70256)<br/>Anti-ADAMTS4 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

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