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ACVR1C (Internal) antibody

Activin receptor type-1C
Activin receptor type IC (ACTR-IC)
Activin receptor-like kinase 7 (ALK-7)
ACVR1C, Activin Receptor-like Kinase, ACVRLK7, ALK7
Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.

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Ref : 00015636

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Product Code pab70243
Immunogen Synthetic 16 amino acid peptide from internal region of human ACVR1C. Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Gibbon (100%), Monkey (100%), Bovine (100%), Bat (100%), Pig (100%), Marmoset (94%), Elephant ( ...
Target Specificity Reacts with human ACVR1C. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Accession Number Q8NER5
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human
Labelling None
Conc. / Activity 1 mg/ml
Form Antigen affinity purified
Constituents PBS
Preservatives NaN3 0.1%
Storage Long term: -70°C; Short term: +4°C
Applications IHC - Paraffin sections
Working dilutions IHC - P (5 µg/ml)
Research areas Apoptosis,Kinases and phosphatases,Signal transduction
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IHC : ACVR1C (Internal) antibody<br/>(pab70243)<br/>Anti-ACVR1C antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

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