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ACVR1 / ALK2 (Internal) antibody

Activin receptor type-1
Activin receptor type I (ACTR-I)
Activin receptor-like kinase 2 (ALK-2)
Serine/threonine-protein kinase receptor R1 (SKR1)
TGF-B superfamily receptor type I (TSR-I)
ACVR1, Activin A receptor type I, Activin A receptor-like kinase 2, Actr1, ACTRI, ActRIA, ACVR1A, ACVRLK2, ALK2, FOP, Tsk7L, TSRI
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin. May be involved for left-right pattern formation during embryogenesis.
Involved in BMP signaling pathway.

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Ref : 00020288

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Product Code pab72611
Immunogen Synthetic peptide C-RKFKRRNQERLNPRD from an internal region of human ACVR1 / ALK2 (NP_001096.1). Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Gibbon (100%), Monkey (100%), Marmoset (100%), Mouse (100%)
Target Specificity Reacts with human ACVR1 / ALK2. Cross reacts with canine, mouse and rat protein.
Name ACVR1 / ALK2
Accession Number Q04771
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Goat
Species Human, Mouse, Rat, Canine
Labelling None
Appearance Liquid
Conc. / Activity 0.5 mg/ml
Form Antigen affinity purified
Constituents TBS, pH 7.3, BSA 0.5%
Preservatives NaN3 0.02%
Storage Store at -20°C. Minimize freezing and thawing.
Applications Western Blot, IHC - Paraffin sections, ELISA
Working dilutions ELISA (1:128000), IHC-P (4 µg/ml), WB (0.3 - 1 µg/ml)
Research areas Cell cycle,Kinases and phosphatases,Signal transduction
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IHC : ACVR1 / ALK2 (Internal) antibody<br/>(pab72611)<br/>Anti-ACVR1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 4 µg/ml.

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