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Ambra1 antibody

Activating molecule in BECN1-regulated autophagy protein 1
autophagy/beclin 1 regulator 1
Gene name: Ambra1, Kiaa1736
Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation

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Price From: €164.00
Ref : 00013214

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Product Code pab0224
Immunogen Synthetic peptide derived from N-term domain of the mouse Ambra 1 protein.
Target Specificity Reacts with mouse 120 kDa Ambra1 protein. Cross reacts with human and rat protein.
Name Activating molecule in BECN1-regulated autophagy protein 1 (Ambra1)
Uniprot ID Q9C0C7
Gene ID 55626
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human, Mouse, Rat
Labelling None
Appearance Lyophilized powder
Form Antiserum
Preservatives None
Recommendations Must be reconstituted in distilled water.
Storage Lyophilized powder stable for a minimum of 2 years at -20°C.
Store reconstituted antibodies at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Applications Western Blot, Immunohistochemistry, Immunofluorescence, ELISA, Electron microscopy
Working dilutions Optimal dilution should be determined by the end user.
Research areas Cell metabolism,Neurology
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* AS Puebla, Lysosome-dependent cell death: molecular players and implications for disease, PhD thesis in biology, director P Boya, University Complutense of Madrid, 2019 (IF, Ms)
* Rodríguez-Muela N et al. Cell Death Differ. 2015 Mar,22(3):476-87.(IHC-F, Ms)
* Pagliarini V et al. Cell Death Differ. 2012 Sep,19(9):1495-504. (WB, Hu)
* Paronetto M.P et al. Peptidic and peptidomimetic compound for regulating autophagy. US Patent Application. 2011 Nov : 20110281804.
* Armstrong J.L. et al. Clin Cancer Res. 2011 Apr 15,17(8):2216-26.(WB, Hu)
* Di Bartolomeo al. J Cell Biol. 2010 Oct 4,191(1):155-68.(IF, EM, Hu)
* Fimia G.M. et al. Nature. 2007 Jun 28,447(7148):1121-5.

IF: Ambra1 antibody<br/>(pab0224)<br/>Anti-Ambra1 antibody IF staining of human fibroblasts expressing full length Ambra1.

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