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ACIN1 / Acinus antibody

Apoptotic chromatin condensation inducer in the nucleus (Acinus)
ACIN1, ACINUS, ACN, DKFZp667N107, fSAP152, KIAA0670
Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Induces apoptotic chromatin condensation after activation by CASP3. Regulates cyclin A1, but not cyclin A2, expression in leukemia cells.

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Ref : 00015632

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Product Code pab70239
Immunogen Synthetic peptide from human ACIN1 / Acinus.
Target Specificity Reacts with human AcinusL (C terminal part), which are identical to those of mouse Acinus.
Name ACIN1 / Acinus
Accession Number Q9UKV3
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human
Labelling None
Appearance Liquid
Form Antigen affinity purified
Constituents PBS
Preservatives NaN3 0.02%
Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
Applications Western Blot, IHC - Paraffin sections, Immunocytochemistry, ELISA
Working dilutions ELISA, ICC, IHC - P (5 µg/ml), WB
Research areas Apoptosis,Nuclear signaling
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IHC : ACIN1 / Acinus antibody<br/>(pab70239)<br/>Anti-ACIN1 / Acinus antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 µg/ml.

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