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ACAN / Aggrecan (N-Terminus) antibody

Aggrecan core protein
Cartilage-specific proteoglycan core protein (CSPCP)
Chondroitin sulfate proteoglycan core protein 1 (Chondroitin sulfate proteoglycan 1)
Gene name : ACAN, AGC1, CSPG1, MSK16
AGC1, AGCAN, Aggrecan 1, CSPGCP, Mcspg, Mgsk16, SEDK
Crucial component of the extracellular matrix of cartilagenous tissue. Mutated form of Aggrecan is involved in skeletal dysplasia and spinal degeneration.

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Ref : 00016825

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Product Code pab70805
Immunogen Synthetic 18 amino acid peptide from N-terminus of human ACAN / Aggrecan. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Hamster, Pig (100%); Mouse, Rat, Bovine, Panda, Horse (94%); Dog, Elephant (89%); Bat (83%).
Target Specificity Reacts with Aggrecan from Human, Gorilla, Monkey, Hamster, Pig. Predicted to cross react with Mouse, Rat, Bovine, Horse. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except NCAN (56%).
Name ACAN / Aggrecan
Uniprot ID P16112
Gene ID 176
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human, Hamster, Monkey
Labelling None
Appearance Liquid
Conc. / Activity 1 mg/ml
Form Antiserum
Constituents PBS
Preservatives NaN3 0.1%
Storage Long term: -70°C; Short term: +4°C
Applications IHC - Paraffin sections
Working dilutions Optimal dilutions should be determined by the end user.
The following are guidelines only:
IHC - P (7 µg/ml)
Research areas Cell biology,Vesicle trafficking
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IHC : ACAN / Aggrecan (N-Terminus) antibody<br/>(pab70805)<br/>Anti-ACAN / Aggrecan antibody IHC of human bone, cartilage. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

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