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AADAT (Internal) antibody

Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial (KAT/AadAT)
2-aminoadipate aminotransferase
2-aminoadipate transaminase
Alpha-aminoadipate aminotransferase (AadAT)
Kynurenine aminotransferase II
Kynurenine--oxoglutarate aminotransferase II
Kynurenine--oxoglutarate transaminase 2
Kynurenine--oxoglutarate transaminase II
Gene name : AADAT, KAT2, KATII
Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro).

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Ref : 00015618

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Product Code pab70225
Immunogen Synthetic 17 amino acid peptide from internal region of human AADAT. Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Gibbon (100%), Marmoset (100%), Monkey (88%), Dog (82%), Elephant (82%).
Target Specificity Reacts with human AADAT. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except TARSL2 (47%).
Accession Number Q8N5Z0
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human
Labelling None
Appearance Liquid
Conc. / Activity 1 mg/ml
Form Antigen affinity purified
Constituents PBS
Preservatives NaN3 0.1%
Storage Store at 4°C for short term applications. For long term storage, aliquot and store at -20°C.
Applications IHC - Paraffin sections
Working dilutions IHC - P (5 µg/ml)
Research areas Cell metabolism
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IHC : AADAT (Internal) antibody<br/>(pab70225)<br/>Anti-AADAT antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

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